作者的目的在于明确非小细胞肺癌(NSCLC)患者在确定接受手术前是否应该先进行脑部核磁共振(MR)检查。回顾性分析结果显示，在646例NSCLC患者中，6.3%发生肿瘤脑转移，且大多发生在术后1年。腺瘤亚型和确诊时已处于早期的NSCLC患者更容易发生转移。据估算，使用术前MRI检查，通过评估体积倍增时间，术前MR成像能够发现大多数(71%)的肿瘤脑部转移。
作者认为，所有NSCLC患者均应该行术前MRI检查，以确定是否发生脑转移。
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The authors of this paper aimed to establish whetherpreoperative brain imaging with magnetic resonance (MR) should be performedprior to definitive surgery for NSCLC. They retrospectively found that, in 646patients, 6.3% developed brain metastases postoperatively and that most ofthese occurred within 1 year of surgery. Patients with an adenocarcinomasubtype and those who were considered early stage at the time of diagnosis weremore likely to develop metastasis. It was estimated using volume doubling timesthat most of the brain metastases (71%) could have been detected withpreoperative MR imaging.
