中枢神经系统疾病领域 7 月重磅突破盘点

阿兹海默病患者组织中的 Tau 纤维结构获得解析

    淀粉样蛋白沉积 (amyloid plaque) 和神经纤维缠结 (neurofibrillary tangle)是阿兹海默病 (Alzheimers disease

    [2] Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia

    [3] Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinsons disease

    [4] Rare coding variants in PLCG2, ABI3, and TREM2implicate microglial-mediated innate immunity in Alzheimer's disease

    [5] C9orf72 expansion disrupts ATM-mediated chromosomal break repair