我最近在看有关一种原发性免疫缺陷病的文章，讲的是高IgM综合征，说高IgM综合征是一种heterogenous disorder，请问大家heterogenous disorder是什么意思啊？字面上是异质性疾病，但是含义是什么啊？很含糊啊！下面是上下文！
The hyper immunoglobulin M (IgM) syndrome(HIGM), characterized by recurrent infections, low serum IgG and IgA, normal or elevated IgM, and defective class switch recombination and somatic hypermutation, is a “
heterogenous disorder” with at least 5 distinct molecular defects, including mutations of the genes coding for the CD40 ligand (CD40L) and IKK-gamma (NEMO) genes, both X-linked; and mutations of CD40, activation-induced cytidine deaminase (AICDA), and uracil-DNA glycosylase (UNG), associated with autosomal recessive HIGM syndromes.
[ 此帖被eleven1113在2009-08-22 08:28重新编辑 ]
